Research Scientist II, Oncology Drug Discovery

Responsibilities include, but are not limited to:

• Generates hypotheses to test, troubleshoots issues and designs and executes the next set of experiments with some input from senior lab members/manager.
• Works independently and as a part of a team to design, execute, and analyze in vitro experiments to profile small molecules and biologics and elucidate mechanisms of action
• Executes cell and molecular biology assays (e.g. cell titer glo, flow cytometry, JESS, western blot, MSD, HTRF)
• Cultures cells using sterile technique including genetic engineering and validation of cell lines
• Uses laboratory automation equipment (liquid handlers, plate readers, dispensers) to perform screens
• Maintains an organized and detailed record of all experiments
• Works collaboratively across teams and trains other members of team in areas of technical expertise as needed.
• Clearly communicates findings and presents research to multidisciplinary project teams
• Supports lab operations including management of materials, maintenance of instruments, and general lab duties

Minimum requirements:

• BS/MS Degree in biology or related field
• Minimum 2+ years of bench work experience in a cancer biology lab
• Demonstrated ability to analyze, interpret and present data in a clear manner and use data to generate new hypotheses
• Hands-on experience with cellular assay development & execution
• Highly self-motivated, collaborative team worker with exceptional organizational skills and curiosity to expand and diversify skillsets

Desirable experience:

• Understanding of drug discovery optimization processes
• Experience with discovery of antibody-drug-conjugates
• Previous industry experience preferred